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猪苓多糖是中药猪茯苓(Polyporus Umbellatus)的提取物。由于它对肿瘤及肝炎的治疗作用,引起有关学者的关注。在对其作用机理的研究中,曾报道它能增加荷瘤动物的PFC数目。本研究室曾用体外药物直接作用方法,证明猪苓多糖是一种非T细胞促有丝分裂素,即对Balb/C鼠和祼鼠脾细胞均有同样的促有丝分裂作用,而T细胞在此反应中不起作用。在此基础上我们用猪苓多糖腹腔注射,观察正常小鼠脾
Polyporus umbellatus polysaccharide is an extract of Polyporus Umbellatus. Because of its therapeutic effects on tumors and hepatitis, it has attracted the attention of relevant scholars. In the study of its mechanism of action, it has been reported that it can increase the number of PFCs in tumor-bearing animals. In this laboratory, we used the direct action of drugs in vitro to prove that polyporus umbellatus polysaccharide is a non-T cell mitogen, ie, it has the same mitogenic effect on Balb/C mice and spleen cells of hamsters, and T cells react in this way. Does not work. On this basis, we used intraperitoneal injection of polyporus polysaccharide to observe the normal mouse spleen