论文部分内容阅读
作者等对46例视网膜色素变性病人(RP),作IgM、类风湿因子(RF)、循环性免疫复合物(CIC)和补体C_3、C_4、CH_(50)的测定,结果发现46例中仅有2例IgM升高。3例出现RF,43.5%病人出现CIC、C_3、C_4和CH_(50)的水平与100例健康对照组比较明显下降(P<0.001);并发现C_3下降与CIC增加、C_4下降与CIC增加及CH_(50)下降与CIC增加均有显著关系(P<0.01,P<0.01,P<0,001)。讨论中指出CIC存在具有局限性诊断价值,但CIC存在不总是免疫复合物疾病的特征。为了说明免疫复合物疾病,需了解疾病的临床活动力与CIC水平、补体溶血活力、补体成分的功能活力变化的关系或补体降解产物升高的值。本文研究结果发现43.5%的RP病人出现CIE,C_3、C_4水平和CH_(50)活力下降均与CIC增
The author of 46 cases of retinitis pigmentosa patients (RP) for IgM, rheumatoid factor (RF), circulating immune complexes (CIC) and complement C_3, C_4, CH_ (50) of the determination and found that 46 cases of only 2 cases of IgM increased. In 3 cases, the levels of CIC, C_3, C_4 and CH_ (50) in 43.5% patients were significantly decreased compared with those in 100 healthy controls (P <0.001). C 3 decreased and CIC increased, C 4 decreased and CIC increased There was a significant relationship between the decrease of CH_ (50) and the increase of CIC (P <0.01, P <0.01, P <0,001). The discussion pointed to the limited diagnostic value of CIC, but the presence of CICs is not always characteristic of immune complex diseases. To illustrate immune complex diseases, one needs to know the relationship between the clinical activity of the disease and CIC levels, complement hemolysis activity, changes in functional vitality of the complement components, or elevated complement degradation products. The results of this study found that 43.5% of RP patients with CIE, C_3, C_4 levels and CH_ (50) activity decreased with CIC increased