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本文报告我院近两年间应用铋剂、羟氨苄青霉素和甲硝唑联合治疗幽门螺杆菌(HP)阳性消化性溃疡30例的近期疗效及随访结果,探讨短程联合用药根除HP的可行性。 1.对象与方法 1.对象:经胃镜确诊的活动性消化性溃疡且HP尿素酶试验阳性60例。溃疡直径0.3~2cm,溃疡个数≤3个,已排除恶变,无心、肝、肺、肾等严重疾病,无胃手术史及大出血、幽门梗阻等病史。治疗组30例,其中十二指肠溃疡25例。胃溃疡3例,复合性溃疡2例。男26例,女4例,平均年龄37岁;对照组30例,其中十二指肠溃疡26例,胃溃疡3例,复合性溃疡1例,男27例,女3例,平均年龄39岁。两组性别、年龄、病程、溃疡部位、大小及数目、类型具有可比性。
This article reports the recent two years in our hospital bismuth, amoxicillin and metronidazole combined treatment of Helicobacter pylori (HP) positive peptic ulcer in 30 cases of short-term efficacy and follow-up results to explore the feasibility of short-term combination of drug eradication HP. 1. Subjects and methods 1. Subjects: active peptic ulcer confirmed by gastroscope and HP urease test was positive in 60 cases. Ulcer diameter of 0.3 ~ 2cm, the number of ulcers ≤ 3, has ruled out malignant, unmotivated, liver, lung, kidney and other serious diseases, no history of gastric surgery and bleeding, pyloric obstruction and other medical history. Treatment group of 30 cases, including duodenal ulcer in 25 cases. 3 cases of gastric ulcer, 2 cases of complex ulcer. There were 26 males and 4 females, with an average age of 37 years. The control group consisted of 30 cases, including 26 cases of duodenal ulcer, 3 cases of gastric ulcer, 1 case of complex ulcer, 27 males and 3 females with an average age of 39 years . Two groups of gender, age, duration, ulcer site, size and number, type is comparable.