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前文报告几种SH基药物对吐酒石(酒石酸锑钾)中毒具有不同程度的解毒效果,其中以二巰基丁二酸钠的毒性最低,解毒效能最强,並能对抗吐酒石对中枢神经系统的抑制作用。 SH基化合物对吐酒石的解毒作用,一般认为是减低了组织的Sb,增加Sb的排泄。我们推测二巰基丁二酸钠对增加Sb的排泄以及排除组织中的积蓄Sb可能比
The foregoing reports that several SH-based drugs have different detoxification effects on toadstool (antimony potassium tartrate) poisoning, of which sodium dimercaptosuccinate has the lowest toxicity and strongest detoxification activity and can antagonize tartar on the central nervous system System of inhibition. The detoxification of SH-based compounds on tartar is generally believed to reduce the organization’s Sb and increase the excretion of Sb. We speculate that sodium dimercaptosuccinate may increase the excretion of Sb and exclude the accumulation of Sb in the tissue