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作者等以通信调查方法,收集1977～1987年德、意、英,法、瑞士、瑞典和美国等国共15个对胰腺内分泌外科诊治的良性单发性或多发性胰岛细胞瘤396例.剖腹探查手术419次,其中首次手术375次,再次手术44次.再次手术者35例,其中又再次手术者7例,二次以上再手术者2例.再次手术在作者等所在医院进行者19例.在本组病例同期间内,恶性胰岛细胞瘤84例、胰岛细胞增生30例,但都不包括在本组范围内.诊断:临床发作性低血症和Whipple三联症是诊断重要依据.空腹激发试验,即持续禁食达72小时,密切观察低血糖症的出现.低血糖症状出现时即刻抽
The authors collected 396 cases of benign solitary or multiple islet cell tumors diagnosed and treated by pancreatic endocrine surgery from 1977 to 1987 in Germany, Italy, Britain, France, Switzerland, Sweden, and the United States. There were 419 operations, of which 375 were performed for the first time and 44 were performed again. Among them, 35 were re-operations, among which 7 were re-operations and 2 were re-operations. The reoperations were performed in the author’s hospital. In this group of patients within the same period, 84 cases of malignant islet cell tumors, 30 cases of islet cell proliferation, but are not included in the scope of this group. Diagnosis: Clinical seizure hypotension and Whipple Triad is an important basis for diagnosis. Fasting The test, that is, continuous fasting for 72 hours, closely observed the occurrence of hypoglycemia.