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目的总结影像学和肿瘤标志物检查在结直肠癌术前TN分期中应用的研究进展。方法收集国内外有关影像学如超声内镜、CT、MRI以及肿瘤标志物如CEA、CA19-9和CA242在结直肠癌术前TN分期中应用的相关文献并进行综述。结果影像学和肿瘤标志物检查对结直肠癌术前TN分期均有不同的价值,但单独运用的价值均比较有限,联合运用可提高术前TN分期判断的准确率。结论在临床工作中,应根据患者的实际情况,有效结合影像学和多种肿瘤标志物检查来提高结直肠癌术前TN分期判断的准确率,以指导临床治疗及改善患者的预后。
Objective To summarize the research progress of imaging and tumor markers in the preoperative TN staging of colorectal cancer. Methods The related literatures of imaging studies such as endoscopic ultrasonography, CT, MRI, and tumor markers such as CEA, CA19-9, and CA242 in preoperative TN staging of colorectal cancer were collected and reviewed. Results Imaging and tumor marker examination had different values for preoperative TN staging of colorectal cancer, but the value of single use was limited. Combined use of them could improve the accuracy of preoperative TN staging judgment. Conclusion In clinical work, the accuracy of preoperative TN staging judgment for colorectal cancer should be improved based on the actual condition of the patient and combined with imaging and multiple tumor markers to guide clinical treatment and improve the prognosis of patients.