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许多治疗中心对绝经前患早期宫颈癌(ⅠB和ⅡA期)的患者均采取手术治疗而不用放疗。一般行根治性子宫切除术,技术上有一定难度,并可能发生一些严重的合并症。而其淋巴结转移率仅为15%～20%,因而可使多数病人行过分治疗。本文从组织病理学分级和肿瘤细胞DNA含量来估计淋巴转移的危险性。作者对126例ⅠB期鳞癌术后患者进行回顾性分析,将组织石腊块切成30μm的切片供组织病理学分级和流式细胞DNA分析。以肿瘤记分值分为等于或小于14和大于14两组。流式细胞分析以DNA
Many centers treat patients with pre-menopausal early cervical cancer (stage IB and stage IIA) without surgery. General radical hysterectomy, technically a certain degree of difficulty, and may lead to some serious complications. The rate of lymph node metastasis is only 15% to 20%, which allows the majority of patients to over-treatment. This article estimates the risk of lymphatic metastasis based on histopathological grade and tumor cell DNA content. The authors retrospectively analyzed 126 postoperative patients with stage IB squamous cell carcinoma, sliced the tissue paraffin block into 30 μm sections for histopathological grade and flow cytometric DNA analysis. Tumor scores were divided into equal or less than 14 and more than 14 groups. Flow cytometry with DNA