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目的研究阿德福韦酯治疗乙型肝炎肝硬化的治疗效果。方法选取2013年1~12月来医院接受治疗的患有乙型肝炎肝硬化的患者88例,将所有患者均分为试验组和对照组各44例,对照组实行苦参素、甘利欣和利尿药物等进行联合治疗,试验组在对照组基础上服用阿德福韦酯治疗,每天服用10mg,治疗36周后比较2组治疗前后生化指标。结果 2组患者治疗后血浆白蛋白、胆红素等方面与治疗前相比,均得到改善,同时治疗后试验组要优于对照组,比较差异有统计学意义(P<0.05)。结论阿德福韦酯治疗乙型肝炎肝硬化具有良好的治疗效果,可以对患者的病情起到改善作用,值得在实际临床中进行推广。
Objective To study the therapeutic effect of adefovir dipivoxil in the treatment of hepatitis B cirrhosis. Methods Eighty-eight patients with hepatitis B cirrhosis who were hospitalized from January to December in 2013 were enrolled. All patients were divided into experimental group and control group, 44 cases in each group. The control group were treated with oxymatrine, Diuretic drugs and other combination therapy, the experimental group on the basis of the control group taking adefovir dipivoxil treatment, taking 10mg daily, after 36 weeks of treatment compared two groups before and after treatment biochemical indicators. Results After treatment, plasma albumin, bilirubin and other aspects of both groups were improved compared with before treatment, and the experimental group was better than the control group after treatment, the difference was statistically significant (P <0.05). Conclusion adefovir dipivoxil treatment of hepatitis B cirrhosis has a good therapeutic effect, can play an improving role in the patient’s condition, it is worth in the actual clinical promotion.