论文部分内容阅读
目的研究D二聚体和C反应蛋白(CRP)在老年进展性脑梗死患者中的动态变化及其对患者预后的评估价值。方法收集我院125例老年急性脑梗死患者,选择40例非脑血管病患者作为对照组,比较对照组与脑梗死组血清D二聚体和CRP含量的区别;脑梗死患者根据临床表现分为进展组和非进展组,分别检测血清CRP和D二聚体水平并比较差异,结果在老年脑梗死患者中血清CRP和D二聚体水平明显高于对照组(P=0.001);非进展组血清CRP和D二聚体含量明显低于进展组患者(P=0.001)。结论血清CRP和D二聚体水平检测有助于老年进展性脑梗死患者的早期诊断,对预后有一定的评估价值。
Objective To study the dynamic changes of D-dimer and C-reactive protein (CRP) in elderly patients with advanced cerebral infarction and their prognostic value. Methods A total of 125 elderly patients with acute cerebral infarction were collected from our hospital and 40 non-cerebrovascular patients were selected as control group to compare the difference of serum D-dimer and CRP between control group and cerebral infarction group. The patients with cerebral infarction were divided into three groups according to their clinical manifestations The levels of CRP and D dimer in serum of patients with cerebral infarction were significantly higher than those of control group (P = 0.001). The progression-free group and non-progress group were significantly lower than those of control group Serum CRP and D dimer levels were significantly lower in patients with progression (P = 0.001). Conclusion Serum CRP and D dimer levels are helpful for the early diagnosis of elderly patients with progressive cerebral infarction and have a certain value in the prognosis.