表现为中毒性表皮坏死性松解症和严重肝炎的苯妥英过敏反应

• 作 者: 谷秀香
• 出 处: 国外医学.皮肤病学分册
• 发表日期: 1986年05期
• 关键词: 苯妥英 过敏反应 坏死性 局限性癫痫发作 肝炎 毒性 腹股沟部 肺底 腋窝 冲击疗法

作者报告了用皮质激素冲击疗法治疗一例表现为中毒性表皮坏死性松解症和严重肝炎的苯妥英过敏反应病人,获得了良效。患者男性,49岁,黑人。因发热、肺炎和腹痛而转来入院。病人新近由于脑卒中继发局限性癫痫发作于转来入院前22天开始服用苯妥英治疗。入院时体温38.3℃,皮肤正常,右肺底实变。腋窝、上滑车、腹股沟部淋巴结1cm大小,可活动,肝脏长

The authors report that corticosteroid shock therapy was used to treat phenytoin allergic patients, a case of toxic epidermal necrolysis and severe hepatitis, and received good results. Male patient, 49 years old, black. Because of fever, pneumonia and abdominal pain and transferred to hospital. Patients were recently treated with phenytoin 22 days prior to their 22-day admission to hospital due to a secondarily-occurring seizure secondary to stroke. Admission temperature 38.3 ℃, normal skin, right lung bottom solidification. Axillary, on the trolley, inguinal lymph nodes 1cm size, activity, liver length