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呋哺硝胺是一新型 H_2受体阻断剂,其抑酸能力较甲氰咪胍强,作用时间也较长。大量临床研究表明,呋喃硝胺治疗活动期十二指肠球部溃疡及胃溃疡,在疗程4周时的愈合率分别为60～93%及57～76%,与甲氰咪胍疗效相似。停用该药后消化性溃疡的复发率与甲氰咪胍无显著差异。该药还可用于其它高胃酸分泌性疾病。由于呋喃硝胺的副作用较甲氰咪胍少,服药量及次数也较少,故适用于因服甲氰咪胍出现副作用而不能耐受者,也有利于长期用药,预防复发。
Furosemide nitrosamines is a new type of H 2 receptor blocker, its inhibitory capacity is stronger than cetamidine, the action time is longer. Numerous clinical studies have shown that furanitramine treatment of active duodenal ulcer and gastric ulcer in the course of 4 weeks healing rates were 60 to 93% and 57 to 76%, and cimetidine similar efficacy. There was no significant difference in the relapse rate of peptic ulcer with cimetidine after discontinuing the drug. This medicine can also be used for other high acid secretion diseases. Because side effects of nitrofurantamine than cimetidine less medication and the frequency is also less, it is suitable for patients with side effects due to cimetidine can not be tolerated, but also conducive to long-term medication to prevent recurrence.