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关于真菌提取物(植物多糖)的抗肿瘤作用,国内外已有不少研究报告。至于暗黄层孔菌(槐耳),仅有我国民间煎服治疗宫颈癌、食道癌获效的报告,其实验研究资料尚未见到,为此,我室对暗黄层孔菌的抗肿瘤作用进行了初步实验观察。本文报告我们研究暗黄层孔菌提取物对带瘤小鼠的瘤组织、瘤周组织和脾脏影响的形态学观察结果,并初步探讨其作用原理。材料和方法暗黄层孔菌[Fomes fulvus(Scop)Gill]:采自陕西关中地区,经中国科学院微生物研究所鉴定。其提取物由我室生化组制备。动物:昆明种小鼠,雌雄各半,体重23～25克左右。瘤种:腹水型肝癌,自第四军医大学引进,腹水型肉瘤180,自陕西省纺织职工医院引进。
With regard to the anti-tumor effects of fungal extracts (plant polysaccharides), there have been many research reports at home and abroad. As for the yellow-earth hole fungus, the report on the efficacy of the treatment of cervical cancer and esophageal cancer by the Chinese folk decoction only has not been seen yet. For this reason, the anti-tumor activity of our chamber to the Lauromycoccus nidulans The role of preliminary experimental observations. In this paper, we report the morphological observations of the effects of the extract of Conus verticilliata on tumor tissue, tumor tissue, and spleen of tumor-bearing mice, and discuss its principle of action. Materials and Methods Fomes fulvus (Scop) Gill: Collected from the Guanzhong area of Shaanxi Province and identified by the Institute of Microbiology, Chinese Academy of Sciences. The extracts were prepared by our biochemical group. Animals: Kunming mice, male and female, weighing about 23 to 25 grams. Tumor type: ascites type liver cancer, imported from the Fourth Military Medical University, ascites type sarcoma 180, imported from Shaanxi Textile Workers’ Hospital.