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目的:研究剖宫产术后应用舒芬太尼联合地佐辛实施硬膜外自控镇痛的效果。方法:将2015年8月—2017年7月在我院实施剖宫产的150例产妇分为对照组和观察组。对照组间断肌内注射哌替啶进行镇痛。观察组实施舒芬太尼联合地佐辛硬膜外自控镇痛。比较两组细胞免疫功能和发生不良反应的情况。结果:两组镇痛有效率相比,差异无统计学意义(P>0.05)。观察组T_1、T_2、T_3时CD3~+、CD4~+、CD4~+/CD8~+、NK细胞水平高于对照组,差异有统计学意义(P<0.05)。结论:对剖宫产产妇在术后实施舒芬太尼联合地佐辛硬膜外自控镇痛效果好,可减轻术后细胞免疫功能抑制。
Objective: To study the effect of sufentanil combined with dezocine on epidural controlled analgesia after cesarean section. Methods: 150 maternal women who underwent cesarean section in our hospital from August 2015 to July 2017 were divided into control group and observation group. Control group intramuscular injection of pethidine for analgesia. The observation group was administered sufentanil and dezocine in the controlled epidural analgesia. Compare the two groups of cellular immune function and the occurrence of adverse reactions. Results: There was no significant difference in analgesic efficiency between the two groups (P> 0.05). The levels of CD3 ~ +, CD4 ~ +, CD4 ~ + / CD8 ~ + and NK cells in T_1, T_2 and T_3 in observation group were significantly higher than those in control group (P <0.05). Conclusion: The effect of sufentanil combined with dezocine on postoperative analgesia after cesarean section is good, which can reduce the postoperative suppression of cellular immune function.