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目的探讨常规超声结合弹性成像对三阴性乳腺癌的诊断价值。方法选取2010年12月至2012年10月间于我院诊治的149例乳腺癌患者,均行超声结合弹性成像检查后,行雌激素受体、人表皮生长因子受体2和孕激素受体检测。其中三阴乳腺癌(35例)为观察组,非三阴性乳腺癌(114例)为对照组,分析两组患者常规超声结合弹性成像的图像特征及常规超声结合弹性成像对三阴性乳腺癌诊断的准确性。结果观察组图像示边缘有毛刺征占28.6%、后方回声衰减占25.7%、微钙化占48.6%和内部血流低级别占22.9%,均明显低于对照组(分别为54.4%、46.5%、77.2%和41.2%),差异均有统计学意义(均P<0.05)。观察组低血流阻力指数占37.1%、低弹性评分占14.3%均高于对照组(分别为34.2%和9.6%),差异均无统计学意义(均P>0.05)。常规超声结合弹性成像对三阴性乳腺癌诊断的敏感度为94.3%,特异度为95.6%和准确度为95.3%。结论常规超声结合弹性成像在三阴性乳腺癌的诊断中具有重要的临床价值,综合分析患者病灶的形态,可显著提高疾病诊断的准确性,值得临床推广使用。
Objective To investigate the diagnostic value of conventional ultrasound combined with elastography in triple negative breast cancer. Methods From December 2010 to October 2012 in our hospital for diagnosis and treatment of 149 cases of breast cancer patients underwent ultrasound combined with elastography examination, the estrogen receptor, human epidermal growth factor receptor 2 and progesterone receptor Detection. Among them, 35 cases of triple-negative breast cancer (observation group) and non-triple-negative breast cancer (114 cases) served as the control group. The imaging characteristics of conventional ultrasound combined with elastography and conventional ultrasound combined with elastography were analyzed to diagnose triple-negative breast cancer Accuracy Results In the observation group, there were 28.6% burr on the edge, 25.7% attenuation on the posterior echo, 48.6% on the microcalcification and 22.9% on the low level of internal blood flow, which were significantly lower than those in the control group (54.4% and 46.5% , 77.2% and 41.2%, respectively), the differences were statistically significant (all P <0.05). The observation group had low blood flow resistance index of 37.1% and low elasticity score of 14.3%, which was significantly higher than that of the control group (34.2% and 9.6% respectively). There was no significant difference between the two groups (all P> 0.05). Conventional ultrasound combined with elastography has a sensitivity of 94.3%, a specificity of 95.6% and an accuracy of 95.3% for the diagnosis of triple-negative breast cancer. Conclusion Conventional ultrasound combined with elastography has important clinical value in the diagnosis of triple negative breast cancer. Comprehensive analysis of the morphology of the lesion can significantly improve the accuracy of the diagnosis of the disease and is worthy of clinical application.