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脾功能低下的迹象是指外周血出现豪-胶小体(Howell-Jolly bodies)、含铁硷粒小体(pappenheimer bodies)和有核红细胞。本文报告1例血红蛋白(Hb)C病脾肿大患者,血片呈现上述情况,后经手术证实为脾血管肉瘤,实属罕见。患者黑人,男性,54岁,入院时主要表现为左侧上半身间歇性钝痛,体重显著下降,发热38℃,肝轻度肿大,无压痛及黄疸,脾大达平脐有压痛,淋巴结无异常。Hb6.8g,红细胞比积23.5%,MCV72fl,MCH29.9pg,MCHC29.3g/dl,网织红细胞1.7%。血片见靶形细胞、皱摺细胞、小球形细胞及HbC结晶体、有核红细胞、豪-胶小体、含铁硷粒小体。白细
Signs of spleen dysfunction are peripheral blood showing Howell-Jolly bodies, pappenheimer bodies and nucleated erythrocytes. This article reports 1 case of hemoglobin (Hb) C disease splenomegaly patients, blood film showed the above situation, after surgery confirmed splenic angiosarcoma, it is rare. Patients black, male, 54 years old, mainly manifested as intermittent dull pain on the left upper body on admission, significant weight loss, fever 38 ℃, mild enlargement of the liver, no tenderness and jaundice, splenic up to the umbilical tenderness, no lymph nodes abnormal. Hb6.8g, hematocrit 23.5%, MCV72fl, MCH29.9pg, MCHC29.3g / dl, reticulocyte 1.7%. Blood film to see the target cells, wrinkled cells, small spherical cells and HbC crystals, nucleated erythrocytes, ho - gel body, iron alkaline granular material. White