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作者比较了第二代二氢吡啶类钙拮抗剂尼卡地平在高血压和充血性心衰病人体内的血流动力学作用。试验对象为原发性高血压和充血性心衰病人各10例,受试者禁食过夜,先静脉推注尼卡地平1～2mg,接着以每分钟200～ 1000μg的速度静滴尼卡地平30分钟,使血流动力学保持稳态,按一定时间间隔测量受试者的心率和血压以及右房压和肺动脉压,然后算出各项心功能指数。结果:尼卡地平使
The authors compared the second generation dihydropyridine calcium antagonist nicardipine in patients with hypertensive and congestive heart failure hemodynamic effects. The subjects were 10 patients with essential hypertension and congestive heart failure. The subjects were fasted for overnight. The patients were initially given intravenous nicardipine 1 ~ 2mg intravenously and then intravenously injected with nicardipine at the speed of 200 ~ 1000μg per minute Thirty minutes, the hemodynamics remained steady, the subject’s heart rate and blood pressure, and right atrial pressure and pulmonary artery pressure were measured at regular intervals, and then the cardiac function indices were calculated. Results: Nicardipine