【摘 要】
：
目的:探讨肾脏黏液样小管状和梭形细胞癌(Mucinous tubular and spindle cell carcinoma,MTSCC)的临床病理学特点,提高对MTSCC的认识和诊断水平.方法:回顾性分析6例MTSCC患者
【机 构】
：
温州市人民医院病理科 浙江 温州 325041;中山大学附属第一医院 广东 广州 510080;赣州市立医院 江西 赣州 341000
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目的:探讨肾脏黏液样小管状和梭形细胞癌(Mucinous tubular and spindle cell carcinoma,MTSCC)的临床病理学特点,提高对MTSCC的认识和诊断水平.方法:回顾性分析6例MTSCC患者的临床资料,并学习相关文献.结果:6例患者中,女性5例,男性1例,年龄32～65岁,术后随访8～96个月,均无复发及转移.镜下可见肿瘤主要由不同比例的小管结构、梭形细胞及粘液间质构成.肿瘤细胞形态温和,但其中两例局部细胞异型性明显,发生了肉瘤样变.免疫组化显示多数病例CK7、P504S、Vimentin、PAX-8及E-cadherin阳性表达,而CD117、Actin及CD10阴性表达.结论:MTSCC是一种罕见的低度恶性肿瘤,其形态学和免疫组化与肾脏多种肿瘤,尤其是乳头状肾细胞癌有重叠,目前染色体分析有助于诊断.
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