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肾病综合征(NS)患者易引起功、静脉系统血栓形成。近年已能应用放免法测定纤维肽A(FPA),β-血小板球蛋白(β-TG)及血小板因子4(PF_4)。FPA系体内血栓活化的一个灵敏指标。β-TG和PF_4则为血小板血管内活化的特异标志物。为此,作者应用这一新的检测方法研究NS的凝血系统异常。作者收集23例NS患者,男13例,女10例,年龄16～70岁(平均38岁),血清白蛋白值2.52±0.82g/dl,蛋白尿8.18±3.45g/日,血小板数214500±60700/mm~3,其中8例肌酐清除显著降低(53～16ml/分)所有患者在研究期间均未服用
Nephrotic syndrome (NS) patients with easy to cause the power and venous system thrombosis. In recent years, the use of radioimmunoassay can be measured fibrinolipid (FPA), β-thromboglobulin (β-TG) and platelet factor 4 (PF_4). FPA Department of Thrombosis in vivo activation of a sensitive indicator. β-TG and PF_4 are specific markers of platelet activation. To this end, the authors apply this new test to investigate the abnormalities of the coagulation system in NS. The authors collected 23 patients with NS, 13 males and 10 females, aged 16 to 70 years (mean 38 years), serum albumin value 2.52 ± 0.82g / dl, albuminuria 8.18 ± 3.45g / day, platelet count 214500 ± 60700 / mm ~ 3, 8 cases significantly reduced creatinine clearance (53 ~ 16ml / min) all patients were not taken during the study