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成人中慢性肝病相关非炎性肾小球病变的病理特征,表现在肾小球毛细血管壁损害和以IgA为主的系膜沉积。这种病变命名为肝性即肝硬变性肾小球硬化。本文151例肝炎病人中82例HBsAg阳性,69例HBsAg和HbsAb阴性,HBsAg阳性组中39例做HBeAg和HbeAb,其中24例抗原阳性,15例抗体阳性,全组病人分为两组,1组为急性肝脏病包括急性肝炎和重症肝炎,2组为慢性肝脏病,如慢性肝炎、肝硬化及肝硬化合并肝细胞癌。光镜检查发现,在HBV相关群中常观察到毛细血管壁的双轨,(18/82,22.0％P<0.01),尤其HBeAg阳性组(8/24,33.3％),HBV非相关群(3/69,4.3％)、两组对比结果P<0.001。
The pathological features of chronic non-inflammatory glomerulopathy in adults with chronic liver disease are manifested in glomerular capillary wall damage and IgA-based mesangial deposition. This lesion is named hepatic cirrhosis glomerulosclerosis. In this paper, 151 cases of hepatitis patients, 82 cases of HBsAg positive, 69 cases of HBsAg and HbsAb negative, HBsAg positive group of 39 cases of HBeAg and HbeAb, of which 24 cases of positive antigen, 15 cases of antibody positive, the whole group of patients divided into two groups, a group of Acute liver disease including acute hepatitis and severe hepatitis, two groups of chronic liver disease, such as chronic hepatitis, cirrhosis and cirrhosis with hepatocellular carcinoma. Light microscopy found that dual-track capillary walls were observed in HBV-related cohorts (18/82, 22.0%, P <0.01), especially in HBeAg-positive patients (8/24, 33.3% 69,4.3%), the two groups compared P <0.001.