平肝调脂方联合西药治疗高血压合并高血脂随机平行对照研究

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[目的]观察平肝调脂方联合西药治疗高血压合并高血脂疗效。[方法]使用随机平行对照方法,将58例住院及门诊患者按就诊顺序编号方法简单随机分为两组。对照组29例缬沙坦,80mg/次,1次/d,口服;硝苯地平,30mg/次,1次/d,口服。治疗组29例平肝调脂方,决明子、首乌各20g,生山楂、桑寄生、赤芍、茯苓各15g,夜交藤、丹参、牛膝、钩藤各30g,杜仲、黄芩、天麻各12g,益母草25g,水煎500mL,1剂/d,早晚温服;西药治疗同对照组。连续治疗3个月为1疗程。观测临床症状、血压、三酰甘油、胆固醇、不良反应。连续治疗2疗程(6个月),判定疗效。[结果]治疗组显效13例,有效14例,无效2例,总有效率93.10%;对照组显效8例,有效11例,无效10例,总有效率65.52%;治疗组疗效优于对照组(P<0.05)。收缩压、三酰甘油、胆固醇两组均明显改善(P<0.01),治疗组改善优于对照组(P<0.01),舒张压治疗组明显改善(P<0.01),对照组无显著变化(P>0.05)。[结论]平肝调脂方联合西药治疗高血压合并高血脂,疗效满意,值得推广。 [Objective] To observe the therapeutic effect of Pinggan Tiaozhi Recipe combined with western medicine on hypertension and hyperlipidemia. [Methods] Using randomized parallel control method, 58 inpatients and outpatients were randomly divided into two groups randomly according to the sequence number of visiting doctor. The control group, 29 cases of valsartan, 80mg / time, 1 / d, oral; nifedipine, 30mg / time, 1 / d, orally. The treatment group, 29 cases of Pinggan Tiaozhi side, cassia seed, Radix 20g, raw Hawthorn, Sang parasitic, red peony root, Poria 15g, night Kudo, Salvia, Achyranthes, Uncaria each 30g, Eucommia, Scutellaria, Gastrodia 12g, Motherwort 25g, Decoction 500mL, 1 / d, morning and evening warm clothes; western medicine treatment with the control group. Continuous treatment of 3 months for a course of treatment. Clinical symptoms, blood pressure, triglyceride, cholesterol, adverse reactions were observed. Continuous treatment of 2 courses (6 months), determine the efficacy. [Results] In the treatment group, 13 cases were markedly effective, 14 cases were effective, 2 cases were ineffective, and the total effective rate was 93.10%. In the control group, 8 cases were markedly effective, 11 cases were effective and 10 cases were ineffective. The total effective rate was 65.52% (P <0.05). Systolic blood pressure, triglyceride and cholesterol in both groups were significantly improved (P <0.01), the treatment group improved better than the control group (P <0.01), diastolic pressure treatment group significantly improved (P <0.01), the control group had no significant change P> 0.05). [Conclusion] Pinggan Tiaozhi Decoction combined with Western medicine in treating hypertension with hyperlipidemia has satisfactory curative effect and is worth popularizing.
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