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急性白血病伴发中枢神经系统改变,早已为临床工作者所重视。特别是近十年来,由于化疗新药的不断出现,缓解率提高,生存期延长,使得中枢神经系统白血病的发病率由10％增加至60％左右,严重的影响本病的治疗。虽然在治疗后的缓解期伴发中枢神经系统白血病的较多,但以中枢神经系统为首发症状的急性白血病至今报告尚属少见,为进一步探讨中枢神经系统白血病的临床类型、诊断与治疗,现将我院三例报告如下,并提出我们的看法,以供参考。
Acute leukemia with central nervous system changes, has long been valued by clinicians. Especially in the last ten years, due to the continuous appearance of new chemotherapy drugs, the remission rate is increased and the survival period is prolonged, the incidence of central nervous system leukemia is increased from 10% to 60%, which seriously affects the treatment of this disease. Although there are more cases of central nervous system leukemia in the remission period after treatment, acute leukemia with the central nervous system as the first symptom has been reported so far. To further explore the clinical types, diagnosis and treatment of central nervous system leukemia, Three cases of our hospital report as follows, and put forward our views for reference.