Evaluation of non-covalent interaction between Seryl-Histidine dipeptide and cyclophilin A using NMR

• 出 处: Science China(Chemistry)
• 发表日期: 2010年9期
• 关键词: covalent esters carboxyl analogues cleavage constants hydroxyl carbonyl coherenc

Seryl-Histidine dipeptide(Ser-His) has been previously reported to be capable of cleaving DNAs and carboxyl esters,as well as proteins.The protein cleavage mechanism has not been addressed yet.As an initial step of protein cleavage activity,the non-covale