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纤维连接蛋白(Fibronectin)是一种糖蛋白,分子量450,000,以可溶态存在于血浆、体液及许多组织中。纤维连接蛋白可促进纤维母细胞及巨噬细胞与胶原结合,似乎对网内系清除颗粒性物质还具有调理素的作用。巳证实肾小球内含纤维连接蛋白,进行肾小球细胞培养也能产生这种蛋白。有人在某些缺血性和免疫性肾小球疾病观察到肾内纤维蛋白增高。在组织损伤的早期,纤维连接蛋白掺入纤维蛋白网架中,由于ⅫⅠ_2的作用而使之与纤维蛋白交联,这在正常组织修复过程中是很重要的。有人认为,接受血液透析的病人之伤口愈合延迟,故作者对经血液透析治疗的尿毒症患者血浆纤维连
Fibronectin is a glycoprotein with a molecular weight of 450,000 that is soluble in plasma, body fluids and many tissues. Fibronectin promotes the binding of fibroblasts and macrophages to collagen, and appears to act as an opsonin for clearing particulate matter within the net. Has confirmed that glomerular fibronectin, glomerular cell culture can produce this protein. Some people in some ischemic and immune glomerular disease observed increased renal fibrin. In the early stages of tissue damage, fibronectin is incorporated into the fibrin network and is cross-linked to fibrin due to the action of IL-2, which is important in normal tissue repair. Some people think that hemodialysis patients wound healing delayed, so the author of hemodialysis treatment of uremic patients with plasma fibronectin