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目的对准备实施辅助生殖技术的夫妇行染色体检查,探讨该项检查的临床意义。方法对1532例拟行辅助生殖技术者外周血淋巴细胞行染色体常规G显带核型分析,必要时辅做高分辨G带、C带或N带。结果 1532例患者中发现染色体变异者108例(7.05%),染色体异常畸变25例(1.63%),染色体多态性变异83例(5.42%)。结论拟行辅助生殖技术夫妇实行染色体筛查是非常必要的,是提高辅助生殖技术的成功率,降低病残儿发生率的重要保障。
Objective To prepare for the implementation of assisted reproductive technology couples line of chromosome examination to explore the clinical significance of this test. Methods Peripheral blood lymphocytes of 1532 cases assisted with reproductive technology were analyzed by conventional G - banding karyotype analysis, and high resolution G band, C band or N band supplemented when necessary. Results Among the 1532 patients, 108 (7.05%) were found chromosomal aberrations, 25 (1.63%) were abnormal chromosomal aberrations and 83 (5.42%) were chromosomal aberrations. Conclusion It is very necessary for couples to practice assisted reproductive technology to carry out chromosome screening. It is an important guarantee to improve the success rate of assisted reproductive technology and reduce the incidence of disabled children.