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目的：了解中枢神经系统感染时脑脊液中α1－酸性糖蛋白检测的临床意义。方法：采用免疫比浊法检测48例中枢神经系统感染脑脊液中α1－酸性糖蛋白的含量。结果：显示化脑组＞病脑组＞对照组（P均＜0．01），化脑极期高于恢复期（P＜0．01）；当α1－酸性糖蛋白含量≥20mg／L时，对化脑的诊断有较高的特异性。结论：该检测方法对小儿中枢神经系统感染的诊断和鉴别诊断、疗效评价和预后的判断均有重要参考价值。
Objective: To investigate the clinical significance of detecting α1-acidic glycoprotein in cerebrospinal fluid during central nervous system infection. Methods: Immunoturbidimetry was used to detect α1-acid glycoprotein in cerebrospinal fluid of 48 patients with central nervous system infection. Results: Compared with the recovery period (P <0.01), the brain of the brain group showed> brain group> control group (P <0.01) , The diagnosis of brain has a higher specificity. Conclusion: The detection method for diagnosis and differential diagnosis of children with central nervous system infection, efficacy evaluation and prognosis have important reference value.