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探讨 CRF患者 PL G活性 ,以及 AT- PL活性的改变情况 ,及其与血清肌酐含量的关系。方法 :用ACL- 2 0 0型全自动血凝分析仪及原厂配套试剂检测 ,PLG及 α2 - AP均采用发色底物法测定。结果 :CRF患者的 PLG活性为 ( 82 .57± 2 1.17) % ,稍低于正常对照组 ( 90 .4 0± 9.72 ) % ,P>0 .0 5。而患者的 α2 - AP活性 ( 87.6± 12 .10 76) %明显低于正常对照组 ( 10 0 .4± 7.56) % ,P<0 .0 1。PL G活性及 α2 - AP活性均与血清肌酐含量呈明显负相关。结论 :慢性肾功能衰竭尿毒症期患者的 PLG活性及 α2 - AP活性 ,均低于正常人 ,且与血清肌酐含量呈明显负相关。
To investigate the PL G activity and the changes of AT-PL activity in patients with CRF and its relationship with serum creatinine. Methods: The ACL-200 Automated Hemagglutination Analyzer and original reagent kit were used to detect PLG and α2-AP. Results: The PLG activity of CRF patients was (82.57 ± 2.11)%, slightly lower than that of the control group (90.400 ± 9.72)%, P> 0.05. However, the activity of α2 - AP in patients (87.6 ± 12.1076)% was significantly lower than that in the control group (10 ± 4. ± 7.56)%, P <0.01. PL G activity and α2 - AP activity were negatively correlated with serum creatinine. Conclusion: PLG activity and α2 - AP activity in uremic patients with chronic renal failure are both lower than those in normal people and negatively correlated with serum creatinine.