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γ—GT被认为是除AFP以外的肝癌的肿瘤标志场,常见于人类肝癌及化学致癌剂诱发的实验性肝癌中,在自发性肝癌中少见,本文用Tanake氏酶组织化学方法探讨了γ—GT在615小鼠肝、肾组织中的定位与分布,证实其反应特性。γ—GT大量存在于鼠肾皮质、新生鼠肝细胞,而在成年鼠肝细胞中阴性。用同法观察由615小鼠自发性肝癌在同系转种而获得的移植性肝癌细胞,见其胞浆中含有丰富的Y—GT,呈橙红色,在不同细胞内含量不一,多者可聚
γ-GT is considered to be a tumor marker field of liver cancer except AFP, which is common in human liver cancer and chemical carcinogen-induced experimental liver cancer and rare in spontaneous liver cancer. In this paper, γ-GT was investigated by Tanake’s enzymatic histochemical method, GT in 615 mice liver and kidney tissue localization and distribution, confirmed its response characteristics. γ-GT is abundant in rat renal cortex, neonatal rat hepatocytes, and negative in adult rat hepatocytes. Observed by the same method from 615 mice with spontaneous liver cancer transplanted in the homologous transplanted liver cancer cells, see its cytoplasm is rich in Y-GT, orange red, different content in different cells, and more may be Poly