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测定了恶性肿瘤患者（胃癌23例，乳腺癌16例）术前、术后1天及术后10天血液抗凝及纤溶系统多项指标，结果发现肿瘤患者血浆抗凝活性明显降低，手术使其进一步加剧，纤溶活性明显升高，Plg：A明显降低，术后1天上述异常进一步加重，但肿瘤患者本前T-PA低于对照，后渐升至正常，术前PAI高于正常对照，后渐降至正常。随着癌肿的切除和手术创伤的恢复，肿瘤患者抗凝及纤溶系统逐渐恢复至正常水平。
The anticoagulant and fibrinolytic system of blood were determined before surgery, on postoperative day 1 and on postoperative day 10 in patients with malignant tumor (23 cases of gastric cancer and 16 cases of breast cancer). The results showed that the plasma anticoagulant activity was significantly reduced in patients with cancer. To further aggravate it, the fibrinolytic activity was significantly increased, Plg:A was significantly decreased, and the above abnormalities were further aggravated on the 1st day after surgery. However, the tumor patient’s previous T-PA was lower than the control, and then gradually increased to normal. The preoperative PAI was higher than Normal controls gradually return to normal afterwards. With the removal of cancer and the recovery of surgical trauma, the anticoagulant and fibrinolytic system of cancer patients gradually returned to normal levels.