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目的比较胰岛素泵持续皮下注射(CSⅡ)与每日多次皮下注射胰岛素(MS Ⅱ)强化治疗2型糖尿病(T2DM)患者围手术期中的疗效差别。方法78例围手术期2型糖尿病患者随机分为CSII组40例、MS Ⅱ组38例进行观察。结果CSⅡ组治疗达到理想血糖所用的时间及胰岛素用量少于MS Ⅱ组(P<0.01),血糖达标率优于MS Ⅱ组(P<0.05或P<0.01)。结论T2DM患者围手术期应用CSⅡ治疗高血糖控制效果显著,能更快达到靶血糖水平、减少低血糖发生,使患者安全度过围手术期。
Objective To compare the efficacy of perioperative period in patients with type 2 diabetes mellitus (T2DM) treated with insulin pump continuous subcutaneous injection (CS Ⅱ) and multiple daily subcutaneous injections of insulin (MS Ⅱ). Methods Seventy eight perioperative patients with type 2 diabetes were randomly divided into CSII group (40 cases) and MS Ⅱ group (38 cases). Results The time and insulin dosage for CS Ⅱ group were less than those of MS Ⅱ group (P <0.01), and the blood glucose compliance rate was better than that of MS Ⅱ group (P <0.05 or P <0.01). Conclusions The perioperative application of CSⅡ in patients with T2DM has a significant effect of controlling hyperglycemia, reaching target blood glucose level more quickly and reducing the incidence of hypoglycemia, which makes the patients safely perioperatively.