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目的探讨注射用头孢哌酮钠舒巴坦钠治疗急性尿路感染的临床疗效。方法 60例急性尿路感染患者,随机分为治疗组和对照组,各30例。治疗组给予注射用头孢哌酮钠舒巴坦钠治疗,对照组给予乳酸左氧氟沙星氯化钠注射液治疗。观察两组疗效。结果治疗组停药后第1、7天的临床有效率均高于对照组(P<0.05);治疗组在用药第4天、停药后第1、7天的细菌学有效率均高于对照组(P<0.05);治疗后两组血浆降钙素原、C反应蛋白均较治疗前下降,治疗组下降更明显,差异均具有统计学意义(P<0.05)。结论注射用头孢哌酮钠舒巴坦钠治疗急性尿路感染效果好、安全性高,可作为首选治疗方案。
Objective To investigate the clinical efficacy of cefoperazone sodium and sulbactam sodium for the treatment of acute urinary tract infection. Methods Sixty patients with acute urinary tract infection were randomly divided into treatment group and control group, with 30 cases in each. The treatment group was treated with cefoperazone sodium and sulbactam sodium for injection, and the control group was given levofloxacin lactate sodium chloride injection. The two groups were observed. Results The clinical effective rates of the first and the seventh day after treatment in the treatment group were significantly higher than those in the control group (P <0.05). The bacteriological efficacies in the treatment group on the 4th day and the 1st and 7th day after stopping were higher than those in the control group (P <0.05). After treatment, the levels of plasma procalcitonin and C-reactive protein in both groups were significantly lower than those before treatment, and the difference between the two groups was statistically significant (P <0.05). Conclusion Cefoperazone sodium and sulbactam sodium for the treatment of acute urinary tract infection with good effect, high safety, can be used as the preferred treatment.