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目的探讨肺炎支原体肺炎患儿应用阿奇霉素联合孟鲁司特钠治疗对血清C反应蛋白(CRP)水平的影响。方法 88例肺炎支原体肺炎患儿,随机分成对照组与观察组,各44例。对照组给予阿奇霉素治疗,观察组给予阿奇霉素联合孟鲁司特钠治疗。对比两组临床疗效及血清CRP水平。结果治疗后,观察组总有效率为95.45%,高于对照组的75.00%(P<0.05);观察组的血清CRP水平显著低于对照组(P<0.05)。结论肺炎支原体肺炎患儿应用阿奇霉素联合孟鲁司特钠治疗效果明显,显著降低了患儿的血清CRP水平,值得推广使用。
Objective To investigate the effect of azithromycin combined with montelukast sodium on serum C-reactive protein (CRP) levels in children with Mycoplasma pneumoniae pneumonia. Methods 88 cases of Mycoplasma pneumoniae pneumonia were randomly divided into control group and observation group, 44 cases in each group. The control group was treated with azithromycin and the observation group was treated with azithromycin and montelukast sodium. The clinical efficacy and serum CRP levels were compared between the two groups. Results After treatment, the total effective rate in the observation group was 95.45%, higher than that in the control group (75.00%, P <0.05). The serum CRP level in the observation group was significantly lower than that in the control group (P <0.05). Conclusion The treatment effect of azithromycin combined with montelukast sodium in children with Mycoplasma pneumoniae pneumonia is obvious, which significantly reduces the level of serum CRP in children and is worth popularizing.