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目的探析慢性阻塞性肺疾病急性加重(AECOPD)合并轻、中度呼吸衰竭患者采用无创呼吸机进行治疗的效果。方法 96例AECOPD合并轻、中度呼吸衰竭患者,随机分成观察组与对照组,每组48例。对照组采取常规方式进行治疗,观察组在对照组基础上采取无创呼吸机进行治疗,对比两组患者临床指标改善情况。结果观察组经过无创呼吸机治疗后呼吸频率(R)、心率(HR)、p H、二氧化碳分压(Pa CO2)、72 h氧分压(Pa O2)等临床指标均优于对照组,比较差异有统计学意义(P<0.05)。结论 AECOPD合并轻、中度呼吸衰竭患者通过无创呼吸机进行临床治疗,可获得较为理想的效果,早期无创正压通气(NPPV)的干预可明显减少间歇正压通气(IPPV)的使用。
Objective To investigate the effect of noninvasive ventilator on patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and mild to moderate respiratory failure. Methods 96 cases of AECOPD with mild to moderate respiratory failure were randomly divided into observation group and control group, 48 cases in each group. The control group was treated by conventional methods. The observation group was treated with noninvasive ventilator on the basis of the control group, and the improvement of clinical indexes was compared between the two groups. Results Compared with the control group, the clinical indexes such as respiratory rate (R), heart rate (HR), p H, PaCO 2 and Pa O 2 in 72h after operation in non-invasive ventilator in observation group were better than those in control group The difference was statistically significant (P <0.05). Conclusions AECOPD with mild to moderate respiratory failure patients can be treated with noninvasive ventilator for satisfactory results. The intervention of early noninvasive positive pressure ventilation (NPPV) can significantly reduce the use of intermittent positive pressure ventilation (IPPV).