论文部分内容阅读
多系统萎缩症是包含几个神经变性的综合征,患此症的患者多伴有尿机能失调,临床上很难与帕金森病相鉴别,本研究的目的是确定两种疾病中特殊的尿动力学与肌电图(EMG)模式,以探讨此二种检查能否有助于对上述两种疾病的鉴别。 62例病人(男37例,女25例)自愿参加此项研究,其中帕金森病患者30例,平均年龄60.8±8.3岁,平均病程10.3±6.5年,平均左旋多巴治疗期9.6±6.3年。平均每日左旋多巴需要量为723±345mg,平均严重程度3.4±0.9(Hoehn和Yahr常模)。多系统萎缩症病人32例,平均年龄为63.3±8.1岁,平均病程7.1±4.6年,其中19例平均每日左旋多巴需要量为538±244mg。研究之前一周停服抗胆碱药物,前一天夜里停服多巴胺类药物。尿动力学评估由泌尿专家实施,应
Multiple system atrophy is a syndrome that involves several neurodegenerative diseases. Patients with this disorder are often associated with urinary dysfunction and are clinically difficult to differentiate from Parkinson’s disease. The purpose of this study was to determine the presence of a specific urinary Kinetics and electromyography (EMG) model to explore whether these two tests can help identify the two diseases. 62 patients (37 males and 25 females) volunteered to participate in this study, of which 30 patients with Parkinson’s disease, the average age of 60.8 ± 8.3 years, the average duration of 10.3 ± 6.5 years, the average levodopa treatment period 9.6 ± 6.3 years . The average daily dose of levodopa was 723 ± 345 mg with an average severity of 3.4 ± 0.9 (Hoehn and Yahr norm). 32 patients with multiple system atrophy, the average age was 63.3 ± 8.1 years, an average duration of 7.1 ± 4.6 years, of which 19 cases average daily levodopa requirement of 538 ± 244mg. Stop taking anticholinergic drugs one week before the study and stop taking dopamine drugs the night before. Urodynamic assessment should be performed by a urologist