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目的:了解我院药品不良反应(ADR)的发生特点,促进临床合理用药。方法:对医院2008～2009年收集的368例ADR报告。分别从患者年龄、ADR性质、药品种类、抗菌药类别、涉及器官系统等方面进行统计分析。结果:368例ADR报告中,严重的ADR 26例,占7.1%;抗菌药和中药制剂ADR报告占前2位;静脉给药引发的ADR 300例占81.5%;ADR表现中以皮肤系统损害最多。结论:应加强药品不良反应监测工作,以减少ADR的发生。
Objective: To understand the characteristics of adverse drug reaction (ADR) in our hospital and to promote rational drug use in clinic. Methods: A total of 368 ADR cases were collected from the hospital from 2008 to 2009. Respectively from the patient’s age, ADR nature, type of drug, antibacterial drug category, involving the organ system and other aspects of statistical analysis. Results: In 368 cases of ADR, 26 cases were serious ADR, accounting for 7.1%. ADR of antibacterial and traditional Chinese medicine accounted for the top two; 300 cases of ADR caused by intravenous injection accounted for 81.5%; ADR showed the most damage to the skin system . Conclusion: Adverse drug reaction monitoring should be strengthened to reduce the occurrence of ADR.