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目的:观察滋阴生液益胎方联合低分子肝素钠治疗羊水过少的临床疗效。方法:选取本院62例羊水过少的初产妇,按照随机数字表法分为治疗组与对照组各31例。对照组给予低分子肝素钠治疗,同时静脉补液1500 m L,治疗组在对照组用药基础上加用滋阴生液益胎方,2组均治疗14天。观察2组治疗前后的羊水指数(AFI)及新生儿窒息程度,比较2组新生儿体质量和剖宫产率。结果:治疗后,2组AFI均较治疗前升高(P<0.01);治疗组的AFI高于对照组(P<0.05)。治疗组有效率83.9%,对照组有效率58.1%,2组比较,差异有统计学意义(P<0.05)。治疗组剖宫产率19.4%,对照组剖宫产率45.2%,2组比较,差异有统计学意义(P<0.05)。2组体质量与新生儿窒息程度比较,差异均有统计学意义(P<0.05)。结论:滋阴生液益胎方联合低分子肝素钠治疗羊水过少,能有效提高AFI,降低剖宫产率和新生儿窒息程度,增加新生儿体质量。
Objective: To observe the clinical efficacy of Ziyin Shengye Yixi Fang combined with low molecular weight heparin in the treatment of oligohydramnios. Methods: 62 cases of oligohydramnios in our hospital were randomly divided into treatment group (n = 31) and control group (n = 31) according to random number table. The control group received low molecular weight heparin sodium treatment, while intravenous rehydration 1500 m L, the treatment group in the control group based on the use of yin yin Sheng Ye Yi fetal side, two groups were treated for 14 days. The amniotic fluid index (AFI) and neonatal asphyxia were observed before and after treatment in two groups. The body mass and cesarean section rate were compared between the two groups. Results: After treatment, the AFI in both groups was significantly higher than that before treatment (P <0.01). The AFI in the treatment group was higher than that in the control group (P <0.05). The effective rate was 83.9% in the treatment group and 58.1% in the control group. There was significant difference between the two groups (P <0.05). Cesarean section rate was 19.4% in the treatment group and 45.2% in the control group. There was significant difference between the two groups (P <0.05). There was significant difference between the two groups in body weight and neonatal asphyxia (P <0.05). Conclusion: Ziyin Shengyinyi Decoction combined with low molecular weight heparin sodium in treating oligohydramnios can effectively improve AFI, reduce the rate of cesarean section and neonatal asphyxia, and increase the body weight of neonates.