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目的研究影响颅咽管瘤手术预后的因素及治疗方法选择。方法回顾性分析84例颅咽管瘤的治疗方式、病理类型及伴发脑积水等与预后的关系。结果次全切除并放疗及全切除者疗效明显优于其它治疗方式，复发病例分别占3／35和2／14，而生存质量优良病例占25／35和9／14。鳞状上皮细胞型的复发比例（2／16）明显低于造釉细胞型（4／16）及混合型（13／52）。伴重度脑积水者疗效最差，复发及死亡病例分别占3／4及1／4。肿瘤体积小及无钙化者预后较好。结论依咽管瘤手术全切及次全切除术后辅以放疗有利于降低肿瘤复发率和改善预后。
Objective To study the factors affecting the prognosis of craniopharyngioma surgery and the treatment options. Methods A retrospective analysis of 84 cases of craniopharyngioma treatment, pathological types and associated with hydrocephalus and prognosis. Results The effect of subtotal resection combined with radiotherapy and total resection was significantly better than other treatments. Recurrences accounted for 3/35 and 2/14, respectively, while excellent quality of life accounted for 25/35 and 9/14. The recurrence rate of squamous epithelial cell type (2/16) was significantly lower than that of ameloblastoma type (4/16) and mixed type (13/52). Patients with severe hydrocephalus had the worst effects, with recurrences and deaths accounting for 3/4 and 1/4, respectively. Small tumors and non-calcified patients have a better prognosis. [Conclusion] The total resection of submandibular pharyngectomy and subtotal radiotherapy combined with subtotal resection can reduce the recurrence rate and improve the prognosis.