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本文研究自拟中药戒得安对吗啡依赖大鼠戒断综合征的治疗效果,并对其是否存在药物身体依赖性作出评价。结果表明,戒得安能明显缓解吗啡依赖大鼠的戒断综合征,戒断症状综合积分及体重减轻情况与无治疗戒断组相比有显著性差异(P<0.01)。实验亦证实戒得安本身无身体依赖性。
This article studies the self-made traditional Chinese medicine jingdean treatment of morphine-withdrawal syndrome in rats, and whether there is any drug-dependent evaluation. The results showed that fluazolam significantly relieved withdrawal syndrome in morphine-dependent rats, and the integrated score of withdrawal symptoms and weight loss had significant difference compared with no treatment withdrawal group (P <0.01). Experiments have also confirmed that there is no physical dependence on Ann.