论文部分内容阅读
目的:探讨C-反应蛋白(CRP)在呼吸道感染性疾病早期诊断中的应用价值,为临床诊断提供参考依据。方法:选取2012年1月-2013年12月会泽县人民医院收治的200例患者作为研究对象,采集2 m L的静脉乙二胺四乙酸(EDTA)抗凝血,使用免疫荧光定量分析仪器进行CRP检测,使用全自动五分类血细胞分析仪器进行白细胞计数检测,观察患者的CRP与白细胞(WBC)计数,分析其特异度与敏感性。结果:病毒感染患者的CRP<30 mg/L,计数<10×109/L;细菌感染患者的CRP>30 mg/L,WBC计数>10×109/L;病毒感染患者的CRP>30 mg/L,WBC计数<10×109/L。CRP与WBC计数的特异度与敏感性相比较,特异度均为100%,但CRP的敏感性要显著优于WBC计数,且差异具有统计学意义(P<0.05)。结论:C-反应蛋白在呼吸道感染性疾病早期诊断中的应用有助于判断患者是否为细菌感染还是其余病原体感染,且具有较高特异度与敏感性。
Objective: To investigate the value of C-reactive protein (CRP) in the early diagnosis of respiratory tract infectious diseases and provide a reference for clinical diagnosis. Methods: A total of 200 patients admitted to Huize County People’s Hospital from January 2012 to December 2013 were enrolled in this study. Venous ethylenediaminetetraacetic acid (EDTA) anticoagulants (2 mL) were collected and quantified by immunofluorescence quantitative analysis The CRP test was carried out. The white blood cell count was detected by automatic five-class blood cell analyzer. The patients’ CRP and WBC counts were counted and their specificity and sensitivity were analyzed. Results: CRP was less than 30 mg / L in virus-infected patients and the count was less than 10 × 109 / L. The CRP was 30 mg / L in patients with bacterial infection and the WBC count was 10 × 109 / L, WBC count <10 × 109 / L. The specificity and sensitivity of CRP and WBC count were all 100%, but the sensitivity of CRP was significantly better than WBC count, and the difference was statistically significant (P <0.05). Conclusion: The application of C-reactive protein in the early diagnosis of respiratory tract infection can help to determine whether the patient is infected with bacteria or the other pathogens, and has high specificity and sensitivity.