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目的 研究单囊型成釉细胞瘤的临床病理及凝集素免疫组织化学特点,探索有助于诊断和鉴别诊断的组织学标记物。方法 对40例单囊型成釉细胞瘤行HE染色及组织学观察;并对其中的25例行荆豆凝集素(UEA1)、兀鹰血凝集素(BSA1)免疫组织化学染色。结果 40例单囊型成釉细胞瘤,组织学上可分为3个亚型:第一型5例(125%),第二型20例(500%),第三型15例(375%);UEA1、BSA1在单囊型成釉细胞瘤、实性或多囊型成釉细胞瘤的上皮中均呈阴性表达,而在牙源性囊肿上皮中呈阳性反应。结论 单囊型成釉细胞瘤具有特征性的临床病理表现;UEA1、BSA1免疫组织化学染色有助于单囊型成釉细胞瘤和牙源性囊肿的鉴别诊断。
Objective To study the clinicopathology and lectin immunohistochemical characteristics of unicystic ameloblastoma and explore the histological markers that are helpful for diagnosis and differential diagnosis. Methods Forty primary cystic ameloblastomas were stained with HE and histological observation. 25 of them were immunohistochemically stained with UEA1 and BSA1. Results Forty patients with single capsule ameloblastoma were histologically divided into 3 subtypes: 5 in the first type (125%), 20 in the second type (500%), and 15 in the third type (375%). ); UEA1, BSA1 were negatively expressed in the cystic ameloblastoma, solid or polycystic ameloblastoma epithelium, and positive in the odontogenic cyst epithelium. Conclusion The single-cell type ameloblastoma has characteristic clinicopathological features. The immunohistochemical staining of UEA1 and BSA1 is helpful for differential diagnosis of unicystic ameloblastoma and odontogenic cyst.