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胎儿含异体蛋白而并不被母体排斥,这一特殊现象多年来一直使生物学家们感到兴趣。近年来已认识某些母亲自身免疫性疾病,尤其是血小板减少症、突眼性甲状腺肿,妊娠类天疱疮(妊娠疱疹)、重症肌无力和系统性红斑狼疮可通过免疫机理影响胎儿,胎儿受累程度与母亲的病情并不成比例。本文对Rh同族免疫不予讨论,尽管胎儿亦可受其母亲抗体的影响,但此抗体与母亲自身免疫性疾病无关。免疫性血小板减少症在免疫性血小板减少症中,IgG抗体可通过胎盘引起胎儿血小板减少及继发出血。继
The fetus contains foreign proteins and is not rejected by the mother, a special phenomenon that has been attracting biologists for years. In recent years, it has been recognized that certain maternal autoimmune diseases, especially thrombocytopenia, exophthalmus goiter, pemphigus vulgaris (herpes gestationis), myasthenia gravis and systemic lupus erythematosus may affect fetuses and fetuses through immune mechanisms The level of involvement is not proportional to the mother’s condition. This article does not discuss Rh homologous immunity, although the fetus may also be affected by its mother’s antibody, but this antibody has nothing to do with the mother’s autoimmune disease. Immune thrombocytopenia In immune thrombocytopenia, IgG antibodies can cause fetal thrombocytopenia and secondary hemorrhage through the placenta. Following