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下肢静脉曲张随着病情进展可引起严重的并发症和致残。本病患者约占苏联全部居民的15～20%,其中2/3是妇女,60～80%病例和妊娠有关。由于近年来对妊娠机体激素的变化和血液动力学等的研究,深化了对本病发病机理的认识。雌激素-孕酮失衡是妊娠下肢静脉曲张的重要原因之一,妊娠早期一昼夜尿中雌二醇水平增高,但到妊娠2、3个月期间,由于卵巢功能旷置,雌激素不足,黄体激素占优势。黄体激素和垂体前叶激素引起子宫血管迅速生长,紧张性下降,流向子宫的血量增加3～4倍,造成躯干下部循环血量和髂部血管口径不相适应,致使下肢血流缓慢,静脉压升高,静脉改建,启动动-静脉分流,增进静脉血管的氧合且使压
Varicose veins as the disease progresses can cause serious complications and disability. The patients account for about 15 to 20% of all residents of the Soviet Union, two thirds of whom are women, and 60 to 80% of cases are related to pregnancy. As in recent years, changes in pregnancy hormone and hemodynamic studies, deepen the understanding of the pathogenesis of this disease. Estrogen-progesterone imbalance is one of the important causes of varicose veins in pregnancy. The urinary estradiol level is increased during the first trimester of pregnancy. However, during the two and three months of pregnancy, due to the exclusion of ovarian function, estrogen deficiency, Dominant. Progesterone and anterior pituitary hormones caused by the rapid growth of uterine blood vessels, tension decreased, the blood flow to the uterus increased 3 to 4 times, resulting in inferior torso blood volume and iliac artery caliber incompatible, resulting in slow blood flow in lower limbs, veins High pressure, vein reconstruction, start the dynamic - venous shunt, to enhance the oxygenation of venous blood and pressure