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肌酸的传统致畸试验按“食品安全性毒性学评价程序和方法”（ＧＢ１５１９３．１４１９９４）进行。实验动物由上海ＢＫ公司提供清洁级ＳＤ大鼠，雌鼠８０只（１９０～２１０ｇ），雄鼠４０只（２００～２２０ｇ），以２∶１配对。孕鼠随机分成５组：肌酸组剂量分别为２００
Traditional teratogenicity test creatine according to “food safety toxicology evaluation procedures and methods” (GB15193.141994). Experimental animals from Shanghai BK company to provide clean grade SD rats, 80 females (190 ~ 210g), male rats (200 ~ 220g), 2: 1 paired. Pregnant mice were randomly divided into 5 groups: creatine group doses were 200