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目的:探讨高原红细胞增多症(H igh altitude polycthaem ia,HAPC)并发胃肠出血(Gastrointestinal bleed ing,GIB)的诱因及防治方法。方法:分析1994年—2003年期间住院确诊为HAPC并GIB的患者56例。结果:诱发因素中幽门螺杆菌(Helicobacter pylori,Hp)感染者阳性率为85.7%,其次服用NSAIDs类药者占42.9%,精神紧张疲劳者占23.2%,呼吸道感染、心肺功能不全及饮酒者分别占14.3%、12.5%、0.71%。结论:Hp感染在HAPC并GIB的诱发因素中占主导地位,Hp感染与服用NSAIDs类药物之间导致GIB起着相互作用,可增加GIB的发生危险性。另外精神紧张疲劳也是诱发HAPC并GIB的重要因素。根除Hp与消除精神高度紧张,是有效防治GIB的措施。
Objective: To investigate the causes and prevention and cure of Hypelocytosis (GIB) complicated with gastrointestinal bleeding (GIB). Methods: Fifty-six patients with HAPC and GIB admitted to hospital from 1994 to 2003 were analyzed. Results: The positive rate of Helicobacter pylori (Hp) infection was 85.7%, followed by 42.9% with NSAIDs, 23.2% with stressful fatigue, respiratory infection, cardiopulmonary insufficiency and drinkers respectively Accounting for 14.3%, 12.5%, 0.71%. CONCLUSION: Hp infection predominates in HAPC and GIB induced factors. Hp infection and administration of NSAIDs lead to GIB interaction, which may increase the risk of GIB. In addition, stressful fatigue is also an important factor inducing HAPC and GIB. Eradication of Hp and eliminate the spirit of high tension, is an effective control measures GIB.