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多巴胺在周围血管上有3种主要药理学作用:低剂量时,其刺激特异的多巴胺能受体,引起强烈的肾脏和肠系膜血管扩张;中等剂量时,其刺激心脏的β肾上腺素能受体,有正性收缩能作用;高剂量时,其有间接拟交感神经作用,引起周围血管收缩。根据多巴胺的上述作用,作者用低剂量盐酸多巴胺静脉内输注对11例少尿患者(年龄10～78岁)进行治疗。全部患者均符合下列标准:连续3小时尿量少于
There are three major pharmacological effects of dopamine on peripheral blood vessels: at low doses it stimulates specific dopaminergic receptors, causing strong renal and mesenteric vasodilation; at moderate doses, it stimulates the beta adrenergic receptors of the heart, A positive contraction can play a role; high dose, it has an indirect sympathomimetic effect, causing peripheral vasoconstriction. Based on the above effects of dopamine, the authors treated 11 oliguric patients (aged 10-78 years) with intravenous infusion of low-dose dopamine hydrochloride. All patients met the following criteria: less than 3 hours urine output