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大肠癌是我国最常见的恶性肿瘤之一,且近年来其发病率呈上升趋势,有研究认为,大肠癌多数系起源于结肠腺瘤。本文对我院1982年至1996年间结肠镜检查发现的大肠息肉和大肠癌进行临床病理分析,旨在对大肠癌与大肠息肉发病关系作一探讨。现报告如下。 临床资料 1982年至1996年的15年中,共行全结肠镜检查3561例,发现大肠息肉488例(564)枚,其中男性289例,女性199例,平均54岁(10～84岁);大肠癌331例(339个癌灶),其中男性170例,女性161例,平均61岁(23～86岁)。大肠癌临床症状主要表现为便血、腹痛、腹泻与便秘交替;大肠息肉主要症状是便血。本组资料中,大肠息肉和大肠癌肿发生部位均以乙状结肠和直肠最为常见,其次为降结肠或升结肠(见附表)。
Colorectal cancer is one of the most common malignancies in China, and its incidence has been on the rise in recent years. Some studies suggest that the majority of colorectal cancers originate from colon adenomas. In this paper, the clinicopathological analysis of colorectal polyps and colorectal cancer found in colonoscopy between 1982 and 1996 in our hospital was conducted to explore the relationship between colorectal cancer and colorectal polyps. The report is as follows. Clinical data In 15 years from 1982 to 1996, 3561 total colonoscopies were examined. 488 cases (564) of colorectal polyps were found, including 289 males and 199 females, with an average age of 54 years (10 to 84 years); 331 cases of colorectal cancer (339 cancer foci), including 170 males and 161 females, averaged 61 years old (23-86 years old). The clinical symptoms of colorectal cancer mainly include alternating blood in the stool, abdominal pain, diarrhea and constipation; the main symptom of colorectal polyps is blood in the stool. In this group of data, the sites of colorectal polyps and colorectal cancers were most common in the sigmoid colon and rectum, followed by descending colon or ascending colon (see attached table).