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对1986年12月-1996年12月10年中收治的37例多发性骨髓瘤(MM)进行分析。年龄40岁以上者占97.3%,中位年龄55岁。起病隐袭,临床表现复杂,误诊率64.9%,误诊时间5-90天,中位误诊时间14天,随着治疗方法的改进,MM生存期明显延长。本组CCOMP+α-干扰素方案治疗14例,平均生存期36个月以上,COMP方案治疗13例,平均生存期15个月,两者差异非常显著(P<0.001)。
Thirty-seven patients with multiple myeloma (MM) who were admitted between December 1986 and December 1996 were analyzed. Aged over 40 years old accounted for 97.3%, the median age of 55 years. Insidious onset, the clinical manifestations of complex, misdiagnosis rate of 64.9%, misdiagnosis time of 5-90 days, median misdiagnosis of time 14 days, with the improvement of treatment, MM survival was significantly prolonged. This group of CCOMP + α-interferon treatment of 14 cases, the average survival of 36 months or more, COMP regimen of 13 cases, the average survival of 15 months, the difference was significant (P <0.001).