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AIM:To investigate the clinical pathologic features ofgastrointestinal leiomyoma and the diagnostic value ofendoscopic ultrasonography (EUS) on gastrointestinalleiomyoma.METHODS:A total of 106 patients with gastrointestinalleiomyoma diagnosed with EUS were studied.The location,size and layer origin of gastric and esophageal leiomyomaswere analyzed and compared.The histological diagnosis ofthe resected specimens by endoscopy or surgery in somepatients was compared with their results of EUS.RESULTS:The majority of esophageal leiomyomas werelocated in the middle and lower part of the esophagus andtheir size was smaller than 1.0 cm,and 62.1% of esophagealleiomyomas originated from the muscularis mucosae.Mostof the gastric leiomyomas were located in the body andfundus of the stomach with a size of 1-2 cm.Almost allgastric leiomyomas (94.2 %) originated from the muscularispropria.The postoperative histological results of 54 patientstreated by endoscopic resection or surgical excision werecompletely consistent with the preoperative diagnosis of EUS,and the diagnostic specificity of EUS to gastrointestinalleiomyoma was 94.7 %.CONCLUSION:The size and layer origin of esophagealleiomyomas are different from that of gastric leiomyomas.Being safe and accurate,EUS is the best method not onlyfor gastrointestinal leiomyoma diagnosis but also for thefollow-up of patients.
A investigation of the clinical pathologic features of gastrointestinal leiomyoma and the diagnostic value of endoscopic ultrasonography (EUS) on gastrointestinal leiomyoma. METHODS: A total of 106 patients with gastrointestinal leiomyoma diagnosed with EUS were studied. The location, size and layer origin of gastric and esophageal leiomyomas were analyzed and compared.The histological diagnosis of the resected specimens by endoscopy or surgery in somepatients was compared with their results of EUS.RESULTS: The majority of esophageal leiomyomas werelocated in the middle and lower part of the esophagus andtheir sizes was smaller than 1.0 cm, and 62.1 % of esophagealleiomyomas originated from the muscularis mucosae. Most of the gastric leiomyomas were located in the body andfundus of the stomach with a size of 1-2 cm. Almost allgastric leiomyomas (94.2%) originated from the muscularispropria.The postoperative histological results of 54 patientstreated by endoscopic resection or surgical excision werecom pletely consistent with the preoperative diagnosis of EUS, and the diagnostic specificity of EUS to gastrointestinal leiomyoma was 94.7%. CONCLUSION: The size and layer origin of esophagealleiomyomas are different from that of gastric leiomyomas. Safe and accurate, EUS is the best method not onlyfor gastrointestinal leiomyoma diagnosis but also for the follow-up of patients.