新杀精剂的目标——宫颈阴道粘液中D-萘氧丙醇胺(心得安)的浓度

• 作 者: 沈琳
• 出 处: 国外医学(计划生育分册)
• 发表日期: 1986年01期
• 关键词: 萘氧丙醇胺 宫颈 粘液 阴道 膜稳定剂 心得安 精子活动力 药物浓度 浓度 血浆

长期以来,用作阴道避孕药的奎宁是膜稳定剂,而D-萘氧丙醇胺与奎宁一样有稳定膜的特性并在试管内能抑制精子活动力。用拭子,冲洗等检查宫颈阴道粘液中的药物浓度是不够的,但用后即扔的阴道吸筒能够重复取样并发展了管理研究的新领域。口服药物后测定宫颈阴道粘液和血浆中的D-萘氧丙醇胺。6名受试者的平均年龄为21.7岁(21～23岁),平均体重为65.2kg(54～78kg)。

Quinine, as a vaginal pill, has long been a membrane stabilizer, and D-naphthalenol has the same stable membrane properties as quinine and inhibits sperm motility in vitro. It is not enough to check the drug concentration in cervical vaginal mucus with swabs, rinsing, etc. However, the disposable vaginal aspirator can sample repeatedly and develop new areas of management research. D-Naphthalene Oxopropanolamine in cervical vaginal mucus and plasma was measured after oral administration. The average age of 6 subjects was 21.7 years (21-23 years) with an average body weight of 65.2 kg (54-78 kg).