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日本的制药工业正处于迅速发展阶段。60年代以前制药工业的研究以有机化学为主轴开发新产品(合成或半合成),而60年代以后,特别是70年代初开始以物理化学为主轴开发新制剂产品,现在日本开发一个新合成药物要化10年时间,化费30亿日元,但研制新制剂只要2～3年及1亿日元。因此,各地药品工业株式会社对制剂研究和生产都很重视,如大正药品工业株式会社是在日本列于第四位的大制药企业,其中大宫分场有1200名职工;四分之三职工从事推销、生产、情报和管理,其余四分之一职工(300名)从事研
Japan’s pharmaceutical industry is in a phase of rapid growth. Research in the pharmaceutical industry before the 1960s focused on the development of new products (synthetic or semisynthetic) based on organic chemistry. Since the 1960s, and especially the early 1970s, the development of new formulations has focused on physical chemistry. Now Japan has developed a new synthetic drug It takes 10 years to spend 3 billion yen, but the development of new preparations as long as 2 to 3 years and 100 million yen. Therefore, various local pharmaceutical companies attach great importance to research and production of pharmaceutical preparations. For example, Taisho Pharmaceutical Co., Ltd. is the fourth-largest pharmaceutical company in Japan with a staff of 1,200 employees in Omiya Branch; three-quarters of workers Engaged in sales, production, intelligence and management, the remaining one-fourth of the workers (300) engaged in research