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他汀类药物为3-羟基-3-甲基戊二酰辅酶A(HMG-CoA)还原酶抑制药,是目前临床上广泛应用防治心血管疾病最有效的药物之一。近年来,多项大规模临床试验结果相继证明,他汀类药物有显著降低血胆固醇水平,可明显降低心血管事件的发生率和死亡率,在冠心病一级、二级防治中具有重要作用。随着他汀类药物的广泛应用和作用机制的深入
Statins are 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, is currently widely used in clinical prevention and treatment of cardiovascular disease, one of the most effective drugs. In recent years, a number of large-scale clinical trial results have shown that statins have significantly lower blood cholesterol levels can significantly reduce the incidence of cardiovascular events and mortality in coronary heart disease, secondary prevention plays an important role. With the widespread use of statins and the mechanism of action in-depth